The role of Glucocorticoid-induced Tumour Necrosis Factor Receptor in developing mouse sympathetic neurons
نویسندگان
چکیده
L. Mckelvey, C. Riccardi, G.W. O’Keeffe. Characterisation of the molecular mechanisms mediating GITR-regulated axonal growth. Neuroscience Ireland 2011, NUI Maynooth, Ireland Laura McKelvey, Humberto Gutierrez, Giuseppe Nocentini, Sean J. Crampton, Carlo R. Riccardi 3 , Gerard W. O’Keeffe. The intracellular portion of GITR enhances NGFpromoted neurite growth through an inverse modulation of Erk and NF-κB signalling. Neuroscience Ireland 2012, RCSI Dublin, Ireland.
منابع مشابه
The intracellular portion of GITR enhances NGF-promoted neurite growth through an inverse modulation of Erk and NF-κB signalling
NF-κB transcription factors play a key role in regulating the growth of neural processes in the developing PNS. Although several secreted proteins have been shown to activate NF-κB to inhibit the growth of developing sympathetic neurons, it is unknown how the endogenous level of NF-κB activity present in these neurons is restricted to allow neurite growth to occur during their normal developmen...
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